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Selected Publications
Pitfalls in performing genome-wide association studies on ratio traits. HGG 2025
Zachary R. McCaw, Rounak Dey, Hari Somineni, David Amar, Sumit Mukherjee, Kaitlin Sandor, insitro Research Team, Theofanis Karaletsos, Daphne Koller, Hugues Aschard, George Davey Smith, Daniel MacArthur, Colm O’Dushlaine, and Thomas W. Soare
https://www.cell.com/hgg-advances/fulltext/S2666-2477(25)00009-0
Temporal dynamics of the multi-omic response to endurance exercise training. Nature 2024
David Amar, Nicole R Gay, Pierre M Jean-Beltran (paper leads), MoTrPAC Study Group.
The mitochondrial multi-omic response to exercise training across tissues. Cell Metabolism 2024
David Amar, Nicole R Gay, David Jimenez-Morales, Pierre M Jean Beltran, Megan E Ramaker, Archana Natarajan Raja, Bingqing Zhao, Yifei Sun, Shruti Marwaha, David Gaul, Steven G Hershman, Ashley Xia, Ian Lanza, Facundo M Fernandez, Stephen B Montgomery, Andrea L Hevener, Euan A Ashley, Martin J Walsh, Lauren M Sparks, Charles F Burant, R Scott Rector, John Thyfault, Matthew T Wheeler, Bret H Goodpaster, Paul M Coen, Simon Schenk, Sue C Bodine, Maléne E Lindholm, MoTrPAC Study Group
https://www.cell.com/cell-metabolism/fulltext/S1550-4131(23)00472-2
Sexual dimorphism and the multi-omic response to exercise training in rat subcutaneous white adipose tissue. Nature Metabolism 2024
Gina M Many, James A Sanford, Tyler J Sagendorf, Zhenxin Hou, Pasquale Nigro, Katie L Whytock, David Amar, Tiziana Caputo, Nicole R Gay, David A Gaul, Michael F Hirshman, David Jimenez-Morales, Malene E Lindholm, Michael J Muehlbauer, Maria Vamvini, Bryan C Bergman, Facundo M Fernández, Laurie J Goodyear, Andrea L Hevener, Eric A Ortlund, Lauren M Sparks, Ashley Xia, Joshua N Adkins, Sue C Bodine, Christopher B Newgard, Simon Schenk
Genetic architecture of cardiac dynamic flow volumes. Nature Genetics 2024
Bruna Gomes, Aditya Singh, Jack W. O’Sullivan, Theresia M. Schnurr, Pagé C. Goddard, Shaun Loong, David Amar, J. Weston Hughes, Mykhailo Kostur, Francois Haddad, Michael Salerno, Roger Foo, Stephen B. Montgomery, Victoria N. Parikh, Benjamin Meder & Euan A. Ashley
Oncogenic context shapes the fitness landscape of tumor suppression. Nature Communications 2023
Lily M Blair, Joseph M Juan, Lafia Sebastian, Vy B Tran, Wensheng Nie, Gregory D Wall, Mehmet Gerceker, Ian K Lai, Edwin A Apilado, Gabriel Grenot, David Amar, Giorgia Foggetti, Mariana Do Carmo, Zeynep Ugur, Debbie Deng, Alex Chenchik, Maria Paz Zafra, Lukas E Dow, Katerina Politi, Jonathan J MacQuitty, Dmitri A Petrov, Monte M Winslow, Michael J Rosen, Ian P Winters
The genetic etiology of periodic limb movement in sleep. Sleep 2023
Jacob L Edelson, Logan D Schneider, David Amar, Andreas Brink-Kjaer, Katie L Cederberg, Zoltán Kutalik, Erika W Hagen, Paul E Peppard, Priscila Farias Tempaku, Sergio Tufik, Daniel S Evans, Katie Stone, Greg Tranah, Brian Cade, Susan Redline, Jose Haba-Rubio, Raphael Heinzer, Pedro Marques-Vidal, Peter Vollenweider, Juliane Winkelmann, James Zou, Emmanuel Mignot
https://academic.oup.com/sleep/article-abstract/46/4/zsac121/6603639
Time trajectories in the transcriptomic response to exercise-a meta-analysis. Nature Communications 2021
David Amar, Malene E Lindholm, Jessica Norrbom, Matthew T Wheeler, Manuel A Rivas, Euan A Ashley
Graphical analysis for phenome-wide causal discovery in genotyped population-scale biobanks. Nature Communications 2021
D Amar, N Sinnott-Armstrong, EA Ashley, MA Rivas
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